Laurence Huang, MD
Professor of Medicine
Research Focus
Dr. Huang is involved in clinical and translational research related to HIV-associated pulmonary disease, primarily Pneumocystis pneumonia (PCP) but increasingly tuberculosis (TB), bacterial pneumonia, chronic obstructive pulmonary disease (COPD) and pulmonary arterial hypertension (PAH). These studies are based on cohorts from San Francisco General Hospital and Mulago Hospital in Kampala, Uganda. The studies involve collaborations with researchers at the National Institutes of Health, University of Cincinnati, University of North Carolina, UCSF, University of Pittsburgh, University of Washington, and University of Colorado and Uganda’s Makerere University. Current research studies include: (1) An multinational cohort study of HIV-associated opportunistic pneumonias to determine the epidemiology, etiology, and outcome of pneumonias in persons with HIV infection; (2) Development and validation of several new molecular applications to study PCP epidemiology, diagnosis, drug-resistance, and host immune response; (3) Development and validation of several new molecular applications to study TB and bacterial pneumonia epidemiology and diagnosis; (4) Comprehensive examination of the composition and function of the lung microbiome in persons with HIV infection; (5) Molecular-epidemiology study that addresses whether PCP results from person-to-person transmission (as has been convincingly demonstrated from animal-to-animal laboratory studies) and whether disease results from reactivation of latent infection or from recent exposure and infection.
Select Publications
| 1) | Huang, L, Quartin, A, Jones, D, and Havlir, DV. Intensive care of patients with HIV infection. New England Journal of Medicine 2006;355(2):173-181. |
| 2) | Morris, A, Wei, K, Afshar, K, and Huang, L. Epidemiology and clinical significance of Pneumocystis colonization. Journal of Infectious Diseases 2008;197:10-17. |
| 3) | Davis, JL, Huang, L, Kovacs, JA, Masur, H, Murray, P, Havlir, DV, Worodria, WO, Charlebois, ED, Srikantiah, P, Cattamanchi, A, Huber, C, Shea, YR, Chow, Y, and Fischer, SH. Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosis. Clin Infect Dis 2009;48(6):725-732. |
| 4) | Cattamanchi, A, Davis, JL, Worodria, W, den Boon, S, Yoo, S, Matovu, J, Kiidha, J, Nankya, F, Kyeyune, R, Byanyima, P, Andama, A, Joloba, M, Osmond, DH, Hopewell, PC, and Huang, L. Sensitivity and specificity of fluorescence microscopy for diagnosing pulmonary tuberculosis in a high HIV prevalence setting. Int J Tuberc Lung Dis 2009;13(9):1130-1136. |
| 5) | Tipirneni, R, Daly, KR, Jarlsberg, LG, Koch, JV, Swartzman, A, Roth, BM, Walzer, PD, and Huang, L. Healthcare worker occupation and immune response to Pneumocystis jirovecii. Emerg Infect Dis 2009;15(10):1590-1597. |
 View PubMed results for Laurence Huang, MD |
Other Links
http://pulmonary.ucsf.edu/faculty/huang.html
http://www.muucsf.org/biog/laurence.html
Education & Training
BA, Johns Hopkins University, Baltimore, MD, 1985
MD, Columbia University College of Physicians and Surgeons, New York, NY, 1989
Internal Medicine Residency, Columbia Presbyterian Medical Center, New York, NY, 1989-1992
Pulmonary and Critical Care Medicine Fellowship, University of California at San Francisco, San Francisco, CA, 1992 – 1995
HIV/AIDS Division Faculty
Oliver Bacon, MD
George Beatty, MD, MPH
Gabriel Chamie, MD
Katerina Christopoulos, MD, MPH
Susa Coffey, MD
Steven G. Deeks, MD
Monica Gandhi, MD, MPH
Elvin H. Geng, MD
Brad Hare, MD
Hiroyu Hatano, MD
Diane Havlir, MD
Rick Hecht, MD
Laurence Huang, MD
Peter Hunt, MD
Mark Jacobson, MD
Vivek Jain, MD
James Kahn, MD
Teri Liegler, PhD
Royce Lin, MD
Annie Luetkemeyer, MD
Paula Lum, MD, MPH
Meg Newman, MD
Chris Pilcher, MD
Elise D. Riley, PhD, MPH
Jacqueline Tulsky, MD
Sheri D. Weiser, MD
Dan Wlodarczyk, MD
Affiliated Faculty
John Baker, MD
Paul Baum, MD, PhD
Edwin Charlebois, PhD
Peter Chin-Hong, MD
Deborah Cohan, MD
Grant Colfax, MD, MPH
Tri Do, MD
Ruth Greenblatt, MD
Sandra Hernandez, MD
Cheryl Jay, MD
Nnemdi Kamanu, MD
Dan Karasic, MD
Jeffrey D. Klausner, MD, MPH
Jeffrey Martin, MD, MPH
Toby Maurer, MD
Joseph M. McCune, MD, PhD
Michelle Roland
Theodore Ruel, MD
Robin Serrahn, MD
Mark Smith, MD, MBA
Serena Spudich, MD
Padmini Srikantiah, MD
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